hpmc capsules vs gelatin capsule vs empty capsule

hpmc capusle raw marterial is hydroxypropyl methycellulose which come from plylmer cellulose ,it is thinked safe for human healty and is used as an option instead of gelatin capsule ,as gelatin capsule raw marterial come from pig or cow and bone,it will some risk such as BSE OR TSE,So many usa  clients choose empty capsule which is hpmc capsule